BDBM50295545 CHEMBL557032::N-(2-phenylcyclopropyl)-4-(3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl)piperidine-1-carboxamide

SMILES O=C(NC1CC1c1ccccc1)N1CCC(CC1)c1nc(no1)-c1cnccn1

InChI Key InChIKey=RUMNCJSUPKAMTM-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50295545   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295545(CHEMBL557032 | N-(2-phenylcyclopropyl)-4-(3-(pyraz...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295545(CHEMBL557032 | N-(2-phenylcyclopropyl)-4-(3-(pyraz...)
Affinity DataIC50:  17nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295545(CHEMBL557032 | N-(2-phenylcyclopropyl)-4-(3-(pyraz...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human sEH in HEK293 cells assessed as conversion of 14,15-epoxyeicosatrienoic acid to 14,15-dihydroepoxyeicosatrienoic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed